Now showing items 1-20 of 20

    • Antibodies recognizing a highly expressed putative antigen of CA-MRSA and methods of use 

      Hook, Magnus; Labandeira-rey, Maria; Bowden, Gabriela M. (United States. Patent and Trademark OfficeTexas A&M University. Libraries, 2012-02-28)
      The present invention provides MSCRAMM® proteins from S. aureus which are putative highly-expressed antigens from methicillin-resistant S. aureus, including communit-associated MRSA (CA-MRSA), and these antigens can thus ...
    • Biosensor compositions and methods of use 

      Bayley, Hagan P.; Howorka, Stefan G.; Movileanu, Liviu (United States. Patent and Trademark OfficeTexas A&M University. Libraries, 2005-07-12)
      Provided are pore-subunit polypeptides covalently linked to one or more sensing moieties, and uses of these modified polypeptides to detect and/or measure analytes or physical characteristics within a given sample.
    • Collagen binding protein compositions and methods of use 

      Hook, Magnus; Patti, Joseph M.; House-Pompeo, Karen; Sthanam, Narayana; Symersky, Jindrich (United States. Patent and Trademark OfficeTexas A&M University. Libraries, 2001-09-11)
      Disclosed are the cna gene and cna-derived nucleic acid segments from Staphylococcus aureus, and DNA segments encoding cna from related bacteria. Also disclosed are Col binding protein (CBP) compositions and methods of ...
    • Crystal structure of Staphylococcus aureus clumping factor A in complex with fibrinogen derived peptide and uses thereof 

      Hook, Magnus; Ko, Ya-ping; Smeds, Emanuel; Ganesh, Vannakambadi K. (United States. Patent and Trademark OfficeTexas A&M University. Libraries, 2012-10-02)
      The present invention provides a method for determining the structure of a microbial surface components recognizing adhesive matrix molecule in complex with fibrinogen, by providing a ClfA complexed with a fibrinogen ...
    • Extracellular matrix-binding proteins from staphylococcus aureus 

      Patti, Joseph M.; Foster, Timothy J.; Josefsson, Elisabet; Eidhin, Deidre Ni; Hook, Magnus A. O.; Perkins, Samuel E. (United States. Patent and Trademark OfficeTexas A&M University. Libraries, 2004-01-20)
      Isolated extracellular matrix-binding proteins, designated ClfB, SdrC, SdrD and SdrE, and their corresponding amino acid and nucleic acid sequences and motifs are described. The proteins, peptides, fragments thereof or ...
    • Extracellular matrix-binding proteins from Staphylococcus aureus 

      Patti, Joseph M.; Foster, Timothy J.; Josefsson, Elisabet; Eidhin, Deidre Ni; Hook, Magnus A. O.; Perkins, Samuel E. (United States. Patent and Trademark OfficeTexas A&M University. Libraries, 2008-06-03)
      Isolated extracellular matrix-binding proteins, designated ClfB, SdrC, SdrD and SdrE, and their corresponding amino acid and nucleic acid sequences and motifs are described. The proteins, peptides, fragments thereof or ...
    • Fibronectin binding protein compositions and methods of use 

      Hook, Magnus; Patti, Joseph M.; House-pompeo, Karen L.; Speziale, Pietro; Joh, Danny; Mcgavin, Martin J. (United States. Patent and Trademark OfficeTexas A&M University. Libraries, 2006-10-31)
      Disclosed are antibodies that block the binding of fibronectin protein to fibronectin. Also disclosed are site specifically-mutated and truncated peptide epitopes derived from the fnbA and fnbB genes of Staphylococcus ...
    • Fibronectin binding protein compositions and methods of use 

      Hook,Magnus; Patti, Joseph M.; House-Pompeo, Karen L.; Speziale, Pietro; Joh, Danny; Mcgavin, Martin J. (United States. Patent and Trademark OfficeTexas A&M University. Libraries, 2004-02-03)
      Disclosed are antibodies that block the binding of fibronectin protein to fibronectin. Also disclosed are site specifically-mutated and truncated peptide epitopes derived from the fnbA and fnbB genes of Staphylococcus ...
    • Method and compositions for inhibiting thrombin-induced coagulation 

      Davis, Stacey; Hook, Magnus A. O. (United States. Patent and Trademark OfficeTexas A&M University. Libraries, 2004-12-28)
      A method of achieving safe and effective treatment or prevention of potentially harmful blood clots, or in inhibiting the coagulation of blood when so desired such as during a wide array of disease conditions including ...
    • Method of preventing T cell-mediated responses by the use of the major histocompatibility complex class II analog protein (map protein) from Staphylococcus aureus 

      Brown, Eric; Lee, Lawrence; Hook, Magnus (United States. Patent and Trademark OfficeTexas A&M University. Libraries, 2006-12-26)
      A method of immunomodulating the T cell response in Staphylococcal bacteria is provided wherein an effective amount of the Map protein from Staphylococcus aureus is administered to a host to prevent or suppress the T cell ...
    • MHC II analog from Staphylococcus aureus 

      Hook, Magnus; Jonsson, Klas; Patti, Joseph M.; Gurusiddappa, Sivashankarappa (United States. Patent and Trademark OfficeTexas A&M University. Libraries, 1997-07-15)
      Staphylococcus aureus can bind a number of different extracellular matrix proteins. Recent studies have shown that one particular Staphylococcus protein has the capacity of binding several different matrix proteins. The ...
    • Polypeptides and polynucleotides from coagulase-negative staphylococci 

      Foster, Timothy J.; Mccrea, Kirk; Hook, Magnus A. O.; Davis, Stacey; Ni Eidhin, Deirdre; Hartford, Orla (United States. Patent and Trademark OfficeTexas A&M University. Libraries, 2010-05-04)
      Methods for treating or preventing infections from coagulase-negative staphylococci using proteins and polypeptides from coagulase-negative staphylococcal bacteria such as S. epidermidis, including proteins designated SdrF, ...
    • Polypeptides and polynucleotides from coagulase-negative staphylococci 

      Foster, Timothy J.; Mccrea, Kirk; Hook, Magnus A. O.; Davis, Stacy; Ni Eidhin, Deirdre; Hartford, Orla (United States. Patent and Trademark OfficeTexas A&M University. Libraries, 2003-10-21)
      Isolated proteins, designated SdrF, SdrG and SdrH, and their corresponding amino acid and nucleic acid sequences are provided which are useful in the prevention and treatment of infection caused by coagulase-negative ...
    • Proteins and polypeptides from coagulaslase-negative staphylococci 

      Foster, Timothy J.; Mccrea, Kirk; Hook, Magnus A. O.; Davis, Stacy; Nieidhin, Deirdre; Hartford, Orla (United States. Patent and Trademark OfficeTexas A&M University. Libraries, 2009-01-06)
      Proteins and polypeptides from coagulase-negative staphylococcal bacteria such as S. epidermidis, including proteins designated SdrF, SdrG and SdrH, and their effective fragments such as their respective A domains, are ...
    • SdrC protein from Staphylococcus aureus and diagnostic kits including same 

      Patti, Joseph M.; Foster, Timothy J.; Joseffson, Elizabet; Eidhin, Deidre Ni; Hook, Magnus A. O.; Perkins, Samuel E. (United States. Patent and Trademark OfficeTexas A&M University. Libraries, 2010-10-19)
      An isolated extracellular matrix-binding protein, designated as SdrC and its corresponding amino acid and nucleic acid sequences and motifs are described. The proteins, peptides, fragments thereof or antigenic portions ...
    • SDRD protein from Staphylococcus aureus and diagnostic kits including same 

      Patti, Joseph M.; Foster, Timothy J.; Josefsson, Elisabet; Eidhin, Deidre Ni; Hook, Magnus A. O.; Perkins, Samuel E. (United States. Patent and Trademark OfficeTexas A&M University. Libraries, 2010-11-16)
      An isolated extracellular matrix-binding protein, designated as SdrD and its corresponding amino acid and nucleic acid sequences and motifs are described. The proteins, peptides, fragments thereof or antigenic portions ...
    • SDRE protein from Staphylococcus aureus and diagnostic kits including same 

      Patti, Joseph M.; Foster, Timothy J.; Josefsson, Elisabet; Eidhin, Deidre Ni; Hook, Magnus A. O.; Perkins, Samuel E. (United States. Patent and Trademark OfficeTexas A&M University. Libraries, 2010-12-21)
      An isolated extracellular matrix-binding protein, designated as SdrE and its corresponding amino acid and nucleic acid sequences and motifs are described. The proteins, peptides, fragments thereof or antigenic portions ...
    • Surface proteins from gram-positive bacteria having highly conserved motifs and antibodies that recognize them 

      Xu, Yi; Hook, Magnus A. O. (United States. Patent and Trademark OfficeTexas A&M University. Libraries, 2004-09-14)
      Isolated peptide sequences and proteins containing these sequences are provided which are useful in the prevention and treatment of infection caused by Gram-positive bacteria. The peptide sequences have been shown to be ...
    • Surface proteins from gram-positive bacteria having highly conserved motifs and antibodies that recognize them 

      Xu, Yi; Hook, Magnus A. O. (United States. Patent and Trademark OfficeTexas A&M University. Libraries, 2007-03-27)
      Isolated peptide sequences and proteins containing these sequences are provided which are useful in the prevention and treatment of infection caused by Gram-positive bacteria. The peptide sequences have been shown to be ...
    • Treatment of Staphylococcus aureus infections utilizing antibodies that bind to fibronectin binding proteins 

      Hook, Magnus; Patti, Joseph M.; House-pompeo, Karen L.; Speziale, Pietro; Joh, Danny; Mcgavin, Martin J. (United States. Patent and Trademark OfficeTexas A&M University. Libraries, 2012-07-03)
      Disclosed are antibodies that block the binding of fibronectin protein to fibronectin. Also disclosed are site specifically-mutated and truncated peptide epitopes derived from the fnbA and fnbB genes of Staphylococcus ...