Now showing items 1-2 of 2

    • Analysis of Genomic Imprinting of UBE3A in Neurons 

      Hillman, Paul Randolph (2015-05-05)
      Angelman syndrome (AS), chromosome 15q11-q13 duplication syndrome (Dup15q), and Prader-Willi syndrome (PWS) are neurodevelopmental disorders associated with dysregulated expression of imprinted genes located within the ...
    • Understanding the Imprinting Mechanism of UBE3A for Therapeutic Intervention 

      Benjamin, Jade Marie (2017-07-21)
      Human chromosome 15q11-q13 contains a cluster of imprinted genes that are associated with a number of neurological disorders that exhibit non-Mendelian patterns of inheritance, such as Angelman syndrome (AS) and Prader-Willi ...