Now showing items 1-20 of 30

    • Adult stem cells/progenitor cells and stem cell proteins for treatment of eye injuries and diseases 

      Prockop, Darwin J.; Oh, Joo Youn; Roddy, Gavin W.; Rosa, Robert; Berkowitz, Barry A. (United States. Patent and Trademark OfficeTexas A&M University. Libraries, 2014-07-22)
      The present invention encompasses methods and compositions for treating an ocular disease, disorder or condition in a mammal. The invention includes a population of mesenchymal stromal cells that possess anti-inflammatory, ...
    • Adult stem cells/progenitor cells and stem cell proteins for treatment of eye injuries and diseases 

      Prockop, Darwin J.; Oh, Joo Youn; Berkowitz, Barry; Roddy, Gavin W.; Rosa, Robert (United States. Patent and Trademark OfficeTexas A&M University. Libraries, 2018-10-23)
      The present invention encompasses methods and compositions for treating an ocular disease, disorder or condition in a mammal. The invention includes a population of mesenchymal stromal cells that possess anti-inflammatory, ...
    • Antibodies recognizing a highly expressed putative antigen of CA-MRSA and methods of use 

      Hook, Magnus; Labandeira-rey, Maria; Bowden, Gabriela M. (United States. Patent and Trademark OfficeTexas A&M University. Libraries, 2012-02-28)
      The present invention provides MSCRAMM® proteins from S. aureus which are putative highly-expressed antigens from methicillin-resistant S. aureus, including communit-associated MRSA (CA-MRSA), and these antigens can thus ...
    • Beta-lactone compounds 

      Smith, Jeffrey W.; Romo, Daniel; Ma, Gil; Zancanella, Manuel (United States. Patent and Trademark OfficeTexas A&M University. Libraries, 2012-09-04)
      The present invention provides compounds having the general structure A, or a pharmaceutically acceptable derivatives thereof: wherein R is an alkyl group, and R1 comprises at least one moiety selected from a group ...
    • Bioinformatic method for identifying surface-anchored proteins from gram-positive bacteria and proteins obtained thereby 

      Hook, Magnus; Xu, Yi; Sillanpaa, Jouko V.; Sthanam, Narayana; Ponnuraj, Karthe; Patti, Joseph M.; Hutchins, Jeff T.; Hall, Andrea; Bowden, Maria G. (United States. Patent and Trademark OfficeTexas A&M University. Libraries, 2009-11-10)
      A bioinformatic method is provided for identifying and isolating proteins with MSCRAMM®—like characteristics from Gram positive bacteria, such as Enterococcus, Staphylococcus, Streptococcus and Bacillus bacteria, which can ...
    • Bioinformatic method for identifying surface-anchored proteins from gram-positive bacteria and proteins obtained thereby 

      Hook, Magnus; Xu, Yi; Sillanpaa, Jouko V.; Sthanam, Narayana; Ponnuraj, Karthe; Patti, Joseph M.; Hutchins, Jeff T.; Hall, Andrea; Bowden, Maria G. (United States. Patent and Trademark OfficeTexas A&M University. Libraries, 2010-12-14)
      A bioinformatic method is provided for identifying and isolating proteins with MSCRAMM®—like characteristics from Gram positive bacteria, such as Enterococcus, Staphylococcus, Streptococcus and Bacillus bacteria, which can ...
    • Collagen binding protein compositions and methods of use 

      Hook, Magnus; Patti, Joseph M.; House-Pompeo, Karen; Sthanam, Narayana; Symersky, Jindrich (United States. Patent and Trademark OfficeTexas A&M University. Libraries, 2001-09-11)
      Disclosed are the cna gene and cna-derived nucleic acid segments from Staphylococcus aureus, and DNA segments encoding cna from related bacteria. Also disclosed are Col binding protein (CBP) compositions and methods of ...
    • Compositions and methods of enhancing immune responses to Eimeria or limiting Eimeria infection 

      Barta, John R.; Berghman, Luc; Shivaramaiah, Srichaitanya; Faulkner, Olivia B.; Bielke, Lisa; Hargis, Billy (United States. Patent and Trademark OfficeTexas A&M University. Libraries, 2018-02-06)
      Vaccine, vectors and methods of using the vaccine vectors to enhance the immune response to an Apicomplexan parasite and reduce the morbidity or mortality associated with subsequent infection are provided herein. The vaccine ...
    • Compositions and methods of enhancing immune responses to Eimeria or limiting Eimeria infection 

      Barta, John R.; Berghman, Luc; Shivaramaian, Srichaitanya; Faulkner, Olivia B.; Bielke, Lisa; Hargis, Billy, (United States. Patent and Trademark OfficeTexas A&M University. Libraries, 2019-06-25)
      Vaccine vectors and methods of using the vaccine vectors to enhance the immune response to an Apicomplexan parasite and reduce the morbidity or mortality associated with subsequent infection are provided herein. The vaccine ...
    • Compositions, methods and uses for a novel family of peptides 

      Jiang, Yi Wei (United States. Patent and Trademark OfficeTexas A&M University. Libraries, 2009-03-03)
      The present invention includes compositions and methods for the characterization and use of novel peptide from Brevibacillus sp., and peptides related thereto, including an isolated and purified, heat stable, amino ...
    • Cross-reactive displacing antibodies from collagen-binding proteins and method of identification and use 

      Hook, Magnus; Xu, Yi; Speziale, Pietro; Visal, Livia; Casolini, Fabrizia; Patti, Joseph M.; Patel, Pratiksha; Domanski, Paul (United States. Patent and Trademark OfficeTexas A&M University. Libraries, 2007-07-10)
      Antibodies to the CNA protein and to other regions from the collagen binding domain, including domain CNA19, are provided, and antibodies produced in this manner have been shown to be cross reactive to both Staphylococcus ...
    • Crystal structure of Staphylococcus aureus clumping factor A in complex with fibrinogen derived peptide and uses thereof 

      Hook, Magnus; Ko, Ya-ping; Smeds, Emanuel; Ganesh, Vannakambadi K. (United States. Patent and Trademark OfficeTexas A&M University. Libraries, 2012-10-02)
      The present invention provides a method for determining the structure of a microbial surface components recognizing adhesive matrix molecule in complex with fibrinogen, by providing a ClfA complexed with a fibrinogen ...
    • DbpA compositions 

      Guo, Betty P.; Hook, Magnus (United States. Patent and Trademark OfficeTexas A&M University. Libraries, 2001-04-10)
      Disclosed are the dbp gene and dbp-derived nucleic acid segments from Borrelia burgdorferi, the etiological agent of Lyme disease, and DNA segments encoding dbp from related borrelias. Also disclosed are decorin binding ...
    • DbpA compositions and methods of use 

      Guo, Betty P.; Hook, Magnus (United States. Patent and Trademark OfficeTexas A&M University. Libraries, 2001-11-06)
      Disclosed are the dbp gene and dbp-derived nucleic acid segments from Borrelia burgdorferi, the etiological agent of Lyme disease, and DNA segments encoding dbp from related borrelias. Also disclosed are decorin binding ...
    • Decorin binding protein compositions 

      Guo, Betty; Hook, Magnus (United States. Patent and Trademark OfficeTexas A&M University. Libraries, 2001-05-08)
      Disclosed are the dbp gene and dbp-derived nucleic acid segments from Borrelia burgdorferi, the etiological agent of Lyme disease, and DNA segments encoding dbp from related borrelias. Also disclosed are decorin binding ...
    • Decorin binding protein compositions and methods of use 

      Guo, Betty; Hook, Magnus (United States. Patent and Trademark OfficeTexas A&M University. Libraries, 1998-12-29)
      Disclosed are the dbp gene and dbp-derived nucleic acid segments from Borrelia burgdorferi, the etiological agent of Lyme disease, and DNA segments encoding dbp from related borrelias. Also disclosed are decorin binding ...
    • Decorin binding protein compositions and methods of use 

      Guo, Betty P.; Hook, Magnus (United States. Patent and Trademark OfficeTexas A&M University. Libraries, 2001-06-19)
      Disclosed are the dbp gene and dbp-derived nucleic acid segments from Borrelia burgdorferi, the etiological agent of Lyme disease, and DNA segments encoding dbp from related borrelias. Also disclosed are decorin binding ...
    • DNA encoding Actinobacillus pleuropneumoniae hemolysin 

      Struck, Douglas K.; Young, Ryland F.; Chang, Yung-Fu (United States. Patent and Trademark OfficeTexas A&M University. Libraries, 1997-06-24)
      This invention discloses the DNA sequences coding for the Actinobacillus pleuropneumonia hemolysin(s). It further discloses a method of producing the A. pleuropneumoniae hemolysin(s) from recombinant cells. It also provides ...
    • Inhibitors of mycobacterium tuberculosis malate synthase, methods of making and uses thereof 

      Freundlich, Joel S.; Sacchettini, James C.; Kriger, Inna V.; Ioerger, Thomas R.; Gawandi, Vijay (United States. Patent and Trademark OfficeTexas A&M University. Libraries, 2014-03-04)
      The present invention provides aryl- or heteroaryl-diketo acid compounds effective to inhibit an activity of a Mycobacterial malate synthase enzyme or to inhibit a malate synthase activity in other bacteria having the ...
    • Method of treating endothelial dysfunction comprising administration of a thrombin peptide derivative 

      Carney, Darrell H.; Olszewska-pazdrak, Barbara; Fossum, Theresa W. (United States. Patent and Trademark OfficeTexas A&M University. Libraries, 2012-12-18)
      Endothelial dysfunction (ED) is associated with a number of diseases and disorders. Agonists of the non-proteolytically activated thrombin receptor can be used in methods to treat ED or ED-related diseases and disorders.