Now showing items 1-20 of 21

    • Adult stem cells/progenitor cells and stem cell proteins for treatment of eye injuries and diseases 

      Prockop, Darwin J.; Oh, Joo Youn; Berkowitz, Barry; Roddy, Gavin W.; Rosa, Robert (United States. Patent and Trademark OfficeTexas A&M University. Libraries, 2018-10-23)
      The present invention encompasses methods and compositions for treating an ocular disease, disorder or condition in a mammal. The invention includes a population of mesenchymal stromal cells that possess anti-inflammatory, ...
    • Adult stem cells/progenitor cells and stem cell proteins for treatment of eye injuries and diseases 

      Prockop, Darwin J.; Oh, Joo Youn; Berkowitz, Barry; Roddy, Gavin W.; Rosa, Robert (United States. Patent and Trademark OfficeTexas A&M University. Libraries, 2017-08-15)
      The present invention encompasses methods and compositions for treating an ocular disease, disorder or condition in a mammal. The invention includes a population of mesenchymal stromal cells that possess anti-inflammatory, ...
    • Adult stem cells/progenitor cells and stem cell proteins for treatment of eye injuries and diseases 

      Prockop, Darwin J.; Oh, Joo Youn; Roddy, Gavin W.; Rosa, Robert; Berkowitz, Barry A. (United States. Patent and Trademark OfficeTexas A&M University. Libraries, 2014-07-22)
      The present invention encompasses methods and compositions for treating an ocular disease, disorder or condition in a mammal. The invention includes a population of mesenchymal stromal cells that possess anti-inflammatory, ...
    • Adult stem cells/progenitor cells and stem cell proteins for treatment of eye injuries and diseases 

      Prockop, Darwin J.; Oh, Joo Youn; Berkowitz, Barry (United States. Patent and Trademark OfficeTexas A&M University. Libraries, 2017-01-17)
      The present invention encompasses methods and compositions for treating an ocular disease, disorder or condition in a mammal. The invention includes a population of mesenchymal stromal cells that possess anti-inflammatory, ...
    • Cancer treatment targeting non-coding RNA overexpression 

      Safe, Stephen; Kim, Kyounghyun (United States. Patent and Trademark OfficeTexas A&M University. Libraries, 2015-02-17)
      Provided herein are methods directed to modulating the pro-oncogenic effects of noncoding RNAs (ncRNAs) through their interactions with specificity protein transcription factors (SpTFs). In one aspect, the disclosure ...
    • Compositions and methods for drug sensitization of parasites 

      Sacchettini, James, C.; Miller, Matthew W.; Wallis, Deann; Zhou, Nian E.; Fossum, Theresa W. (United States. Patent and Trademark OfficeTexas A&M University. Libraries, 2019-03-12)
      Compositions and methods for inhibiting and/or sensitizing or re-sensitizing a parasite to an antiparasitic drug are provided. The compositions can comprise a rifamycin derivative or a pharmaceutically acceptable salt, ...
    • Compositions and methods for drug-sensitization or inhibition of a cancer cell 

      Sacchettini, James; Zhou, Niam; Baker, Dwight; Maxwell, Steven A.; Wallis, Deeann (United States. Patent and Trademark OfficeTexas A&M University. Libraries, 2017-01-10)
      The disclosure provides rifamycin and rifamycin derivative compositions, including rifabutin and rifabutin derivative compositions able to cause drug-sensitization in a cancer cell or inhibition of a cancer cell. The ...
    • Compositions and methods for drug-sensitization or inhibition of a cancer cell 

      Sacchettini, James; Zhou, Niam; Baker, Dwight; Maxwell, Steven A.; Wallis, Deeann (United States. Patent and Trademark OfficeTexas A&M University. Libraries, 2015-09-15)
      The disclosure provides rifamycin and rifamycin derivative compositions, including rifabutin and rifabutin derivative compositions able to cause drug-sensitization in a cancer cell or inhibition of a cancer cell. The ...
    • Compositions and methods for drug-sensitization or inhibition of a cancer cell 

      Sacchettini, James; Zhou, Niam; Baker, Dwight; Maxwell, Steven A.; Wallis, Deeann (United States. Patent and Trademark OfficeTexas A&M University. Libraries, 2018-01-16)
      The disclosure provides rifamycin and rifamycin derivative compositions, including rifabutin and rifabutin derivative compositions able to cause drug-sensitization in a cancer cell or inhibition of a cancer cell. The ...
    • Compositions and methods related to toll-like receptor-3 

      Kao, Cheng C.; Tharachaparamba, Ranjith Kumar (United States. Patent and Trademark OfficeTexas A&M University. Libraries, 2011-11-29)
      The invention relates to compositions and methods related to Toll-like receptor (TLR) polypeptides. In some embodiments, the invention relates to managing TLR3 related diseases. In further embodiments, the invention relates ...
    • Compounds and methods for the treatment of cancer 

      Zingaro, Ralph A.; Zingaro, Ralph A. (United States. Patent and Trademark OfficeTexas A&M University. Libraries, 2012-07-17)
      The present invention provides organic arsenicals which may be used to treat numerous human tumor cell lines, both of solid and hematological origin, as well as against malignant blood cells from patients with leukemia.
    • Control of microbial populations in the gastrointestinal tract of animals 

      Mckenzie, Scott K.; Giletto, Anthony; Hitchens, Duncan G.; Hargis, Billy M.; Herron, Kelly L. (United States. Patent and Trademark OfficeTexas A&M University. Libraries, 2003-02-11)
      The present invention provides a method for controlling microbial populations in the gastrointestinal tract of animals. The method comprises the step of orally administering an effective amount of a peracid to an animal. ...
    • Endocrine therapy for breast cancer: combined treatment with tamoxifen plus alkyl PCDFs 

      Safe, Stephen H. (United States. Patent and Trademark OfficeTexas A&M University. Libraries, 2000-10-24)
      Methods and pharmaceutical combinations for inhibiting estrogen-dependent tumors via the co-administration of antiestrogen triphenylethylenes, including tamoxifen, and alkyl PCDFs.
    • Inhibitors of mycobacterium tuberculosis malate synthase, methods of making and uses thereof 

      Freundlich, Joel S.; Sacchettini, James C.; Kriger, Inna V.; Ioerger, Thomas R.; Gawandi, Vijay (United States. Patent and Trademark OfficeTexas A&M University. Libraries, 2014-03-04)
      The present invention provides aryl- or heteroaryl-diketo acid compounds effective to inhibit an activity of a Mycobacterial malate synthase enzyme or to inhibit a malate synthase activity in other bacteria having the ...
    • Mycophenolic acid analogues as anti-tumor chemosensitizing agents 

      Tsai, Robert Y.; Lin, Tao (United States. Patent and Trademark OfficeTexas A&M University. Libraries, 2016-11-15)
      In some embodiments, the present invention provides methods of treating a tumor in a subject. In some embodiments, the methods may include a step of administering to the subject a therapeutic composition that comprises: ...
    • Occidiofungin formations and uses thereof 

      Smith, James L.; Pruett, Stephen; Austin, Frank; Lu, Shien; Akshaya, Ravichandran; Laihing, Steven (United States. Patent and Trademark OfficeTexas A&M University. Libraries, 2019-04-23)
      Disclosed are occidiofungin formulations and uses thereof for the treatment of proliferative disorders, such as cancer. Methods of producing the disclosed occidiofungin formulations are also provided. Further, methods of ...
    • Perlecan domain V protects, repairs and restores ischemic brain stroke injury and motor function 

      Bix, Gregory J. (United States. Patent and Trademark OfficeTexas A&M University. Libraries, 2015-07-07)
      The disclosed invention relates to the use of perlecan domain V (DV) for the treatment of stroke, traumatic brain injury (TBI) or spinal cord injuries (SCI). In certain embodiments, fusion proteins of DV can be used for ...
    • Prevention of bacterial growth and biofilm formation by ligands that act on cannabinoidergic systems 

      Schetz, John A.; Hoger, Sally A. (United States. Patent and Trademark OfficeTexas A&M University. Libraries, 2015-11-24)
      A group of antimicrobial compounds shows effectiveness for preventing bacterial growth and bio film formation. In particular, the compounds are effective for preventing the growth of gram-positive bacteria, including ...
    • Replacement therapy for dental caries 

      Hillman, Jeffrey D.; Smith, James Leif; Wilson-stanford, Shawanda R. (United States. Patent and Trademark OfficeTexas A&M University. Libraries, 2016-02-16)
      The invention provides recombinant Streptococcus mutans strains that can be used to improve oral health. An embodiment of the invention provides a method of reducing the incidence or severity of dental caries in a dental ...
    • Treatment of stroke using domain V of perlecan 

      Bix, Gregory J. (United States. Patent and Trademark OfficeTexas A&M University. Libraries, 2013-06-18)
      The present invention is drawn to methods of stimulating or enhancing angiogenesis in a patient comprising, administering to said patient a therapeutically effective amount of an endorepellin protein, wherein said endorepellin ...