Now showing items 1-15 of 15

    • Cancer treatment targeting non-coding RNA overexpression 

      Safe, Stephen; Kim, Kyounghyun (United States. Patent and Trademark OfficeTexas A&M University. Libraries, 2015-02-17)
      Provided herein are methods directed to modulating the pro-oncogenic effects of noncoding RNAs (ncRNAs) through their interactions with specificity protein transcription factors (SpTFs). In one aspect, the disclosure ...
    • Compositions and methods for drug sensitization of parasites 

      Sacchettini, James, C.; Miller, Matthew W.; Wallis, Deann; Zhou, Nian E.; Fossum, Theresa W. (United States. Patent and Trademark OfficeTexas A&M University. Libraries, 2019-03-12)
      Compositions and methods for inhibiting and/or sensitizing or re-sensitizing a parasite to an antiparasitic drug are provided. The compositions can comprise a rifamycin derivative or a pharmaceutically acceptable salt, ...
    • Compositions and methods for drug-sensitization or inhibition of a cancer cell 

      Sacchettini, James; Zhou, Niam; Baker, Dwight; Maxwell, Steven A.; Wallis, Deeann (United States. Patent and Trademark OfficeTexas A&M University. Libraries, 2018-01-16)
      The disclosure provides rifamycin and rifamycin derivative compositions, including rifabutin and rifabutin derivative compositions able to cause drug-sensitization in a cancer cell or inhibition of a cancer cell. The ...
    • Compositions and methods related to toll-like receptor-3 

      Kao, Cheng C.; Tharachaparamba, Ranjith Kumar (United States. Patent and Trademark OfficeTexas A&M University. Libraries, 2011-11-29)
      The invention relates to compositions and methods related to Toll-like receptor (TLR) polypeptides. In some embodiments, the invention relates to managing TLR3 related diseases. In further embodiments, the invention relates ...
    • Control of microbial populations in the gastrointestinal tract of animals 

      Mckenzie, Scott K.; Giletto, Anthony; Hitchens, Duncan G.; Hargis, Billy M.; Herron, Kelly L. (United States. Patent and Trademark OfficeTexas A&M University. Libraries, 2003-02-11)
      The present invention provides a method for controlling microbial populations in the gastrointestinal tract of animals. The method comprises the step of orally administering an effective amount of a peracid to an animal. ...
    • Decorin proteoglycan inhibitor of fibrinogen blood clotting 

      Höök, Magnus; Dugan, Tracey A. (United States. Patent and Trademark OfficeTexas A&M University. Libraries, 2006-08-22)
      The present invention provides compositions and methods of inhibiting fibrin(ogen) clot formation by utilizing decorin proteoglycan as an anticoagulating and antithrombotic agent. The decorin proteoglycan comprises a decorin ...
    • Endocrine therapy for breast cancer: combined treatment with tamoxifen plus alkyl PCDFs 

      Safe, Stephen H. (United States. Patent and Trademark OfficeTexas A&M University. Libraries, 2000-10-24)
      Methods and pharmaceutical combinations for inhibiting estrogen-dependent tumors via the co-administration of antiestrogen triphenylethylenes, including tamoxifen, and alkyl PCDFs.
    • Functionalized protein-based materials and their uses 

      Bondos, Sarah; Bayless, Kayla; Matthews, Kathleen; Patterson, Jan; Abbey, Colette; Howell, David; Hsiao, Hao-Ching; Churion, Kelly; Tsai, Shang-Pu; Ramasamy, Sandhya; Porterpan, Dustin; Northern, Keira (United States. Patent and Trademark OfficeTexas A&M University. Libraries, 3/16/2021)
      Embodiments of the invention are directed to Ubx-fusion molecules that maintain their mechanical strength and properties even after being fused with Ubx. Ubx fusions with VEGF and other growth factors, cell signaling ...
    • Method and compositions for inhibiting thrombin-induced coagulation 

      Davis, Stacey; Hook, Magnus A. O. (United States. Patent and Trademark OfficeTexas A&M University. Libraries, 2004-12-28)
      A method of achieving safe and effective treatment or prevention of potentially harmful blood clots, or in inhibiting the coagulation of blood when so desired such as during a wide array of disease conditions including ...
    • Method of treating inflammatory bowel disease by administering a clip-inducing agent 

      Newell, Martha Karen; Harvey, Cassie L.; Tobin, Richard (United States. Patent and Trademark OfficeTexas A&M University. Libraries, 2014-12-09)
      The disclosure relates to methods for treating disorders of the mucosal tract such as the gastrointestinal system by targeting CLIP molecules. The methods are based on that CLIP in the groove of MHC class I or II molecules ...
    • Occidiofungin formations and uses thereof 

      Smith, James L.; Pruett, Stephen; Austin, Frank; Lu, Shien; Akshaya, Ravichandran; Laihing, Steven (United States. Patent and Trademark OfficeTexas A&M University. Libraries, 2019-04-23)
      Disclosed are occidiofungin formulations and uses thereof for the treatment of proliferative disorders, such as cancer. Methods of producing the disclosed occidiofungin formulations are also provided. Further, methods of ...
    • Perlecan domain V protects, repairs and restores ischemic brain stroke injury and motor function 

      Bix, Gregory J. (United States. Patent and Trademark OfficeTexas A&M University. Libraries, 2015-07-07)
      The disclosed invention relates to the use of perlecan domain V (DV) for the treatment of stroke, traumatic brain injury (TBI) or spinal cord injuries (SCI). In certain embodiments, fusion proteins of DV can be used for ...
    • Recombinant virus expressing foreign DNA encoding feline CD86 and uses thereof 

      Winslow, Barbara J.; Cochran, Mark D.; Hash, Stephen; Choi, Insoo; Collisson, Ellen (United States. Patent and Trademark OfficeTexas A&M University. Libraries, 2007-10-09)
      The present invention involves a recombinant virus which comprises at least one foreign nucleic acid inserted within a non-essential region of the viral genome of a virus, wherein each such foreign nucleic acid encodes a ...
    • Treatment of stroke using domain V of perlecan 

      Bix, Gregory J. (United States. Patent and Trademark OfficeTexas A&M University. Libraries, 2013-06-18)
      The present invention is drawn to methods of stimulating or enhancing angiogenesis in a patient comprising, administering to said patient a therapeutically effective amount of an endorepellin protein, wherein said endorepellin ...
    • Use of vitelline protein B as a microencapsulating additive 

      Ficht, Allison R.; Carson, Kenneth; Sheffield, Cynthia; Waite, John Herbert (United States. Patent and Trademark OfficeTexas A&M University. Libraries, 3/23/2021)
      The present invention includes compositions and methods for the use of an encapsulation additive having between about 0.1 to about 30 percent isolated and purified vitelline protein B to provide for mixed and extended ...