Browsing by Department "Biomedical Sciences"
Now showing items 21-40 of 58
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(2015-04-23)Cleft palate (CP) is one of the most common birth defects. It may not be life threatening but many functions, such as feeding, digestion, speech, middle-ear ventilation, hearing, respiration, and facial and dental development, ...
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(2021-08-13)Skeletal growth deficiencies arising from birth defects, injury or disease exist despite advances in therapy; as a public health imperative, this reflects the need for a deeper understanding of its causes. The molecular ...
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(2021-09-01)Epigenetic alterations, such as changes in DNA methylation, histones/chromatin structure, nucleosome positioning, and expression of non-coding RNAs, are recognized among key characteristics of carcinogens; they may occur ...
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(2023-08-03)Hypophosphatasia (HPP) is a rare inherited disorder that is due to inactivation of the tissue-nonspecific alkaline phosphatase (ALP) gene ALPL. There are more than 400 different mutations in the human ALPL gene that ...
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(2021-05-03)Periodontitis and odontogenic abscesses are common dental ailments that affect the ability to obtain sufficient nutrition. Thus, they are important indicators of oral health and quality of life. In this study, oral health ...
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(2021-04-27)Basic fibroblast growth factor (bFGF) is a central growth factor required for cell proliferation, survival, migration, and differentiation. bFGF enhances both the mitogenic and chondrogenic potential of human mesenchymal ...
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(2015-08-10)The prostate is an androgen-dependent male reproductive organ that is comprised of epithelial and stromal compartments. The epithelial compartment contains basal, luminal, and neuroendocrine cells. Two types of prostate ...
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(2010-01-16)Arterial pulse pressure is critically important to a number of diseases such as isolated systolic hypertension, coronary artery disease and heart failure. Determining the cause of increased pulse pressure has been hampered ...
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(2018-01-18)The human brain is responsible for constructing how we perceive, think, and act in the world around us. The organization of these functions is intricately distributed throughout the brain. Here, I discuss how functional ...
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Hepatic Cholesterol Metabolism Drives Enteric Immunity and Development of Necrotizing Enterocolitis (2018-04-05)Necrotizing Enterocolitis (NEC) is a disease of the neonatal gastrointestinal tract related to prematurity, low birth weight and formula feeding that has been linked to imbalances in tolerizing versus inflammatory lymphocytes. ...
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(2013-12-10)Purpose: The purpose of this research was to quantify the number of blood vessels and nerves and mineral apposition rate (MAR) in native bone and compare it to the regenerate bone produced by bone transport distraction ...
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(2022-08-19)Urinary Tract Infections are a global health concern affecting approximately 7-11 million people in the United States annually. Uropathogenic Escherichia coli (UPEC) are the primary etiologic agent of uncomplicated UTIs, ...
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(2019-05-23)Feline chronic enteropathy is a very common disorder with an increasing prevalence over the past decades. It mainly comprises idiopathic inflammatory bowel disease (IBD) and alimentary small cell lymphoma (SCL). Histopathology, ...
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The viral illness coronavirus disease 2019 (COVID-19) has affected millions worldwide since its initial discovery in late 2019. After recovering from the primary viral infection, many have found themselves suffering new, ...
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(2020-07-15)Regeneration of functional dentin remains challenging in regenerative dentistry since it requires a precise control of odontoblast polarization and differentiation. Both biophysical and biochemical factors have been proposed ...
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(1982)A number of known chemical carcinogens were tested as potential inducers of mouse tissue esterases. Only the nitrosamines, DEN and DPN, altered the electrophoretic profiles of esterases in this study. While nitrosamines ...
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The yellow fever mosquito, Aedes aegypti, is a globally distributed mosquito and the primary vector of arthropod-borne viruses (arboviruses) such as dengue, Zika, and chikungunya viruses. These Aedes-borne diseases impose ...
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(2019-04-12)Histamine, synthesized by L-histidine decarboxylase (HDC), is a trophic growth factor that increases biliary damage/proliferation, inflammation, hepatic fibrosis and angiogenesis. Histamine signals through one of four G ...
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(2013-12-17)Hypoxia in the neonate is one of the leading causes of encephalopathy and seizures. Sadly, a significant subset of these children will acquire epilepsy, as their risk increases several-fold even with recovery from the ...
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(2020-03-17)Cholangiocytes are the epithelial cells lining the bile ducts in the liver and the target of cholestatic liver diseases, such as primary sclerosing cholangitis (PSC) and primary biliary cholangitis (PBC). Cholangiopathies ...