Swine and wild boars in Africa, and parts of Europe and Russia continue being decimated by a severe form of hemorrhagic fever known as African Swine Fever (ASF). This viral disease has been responsible for the deaths of millions of swine and poses a significant risk to the United States pork industry since it is easily transmitted across continents. However, there is no vaccine or treatment available and thus, it is important to develop a vaccine that can prevent future infections, and reduce the economic and social impacts resulting from this disease. My research will focus on generating recombinant lentivirus expressing 9GL and CD2v ASFV antigens which will be used to evaluate antigen-specific cytotoxic T cell responses in pigs immunized with recombinant adenoviruses expressing these two antigens.