Browsing by Author "Burghardt, Robert C"
Now showing items 1-20 of 20
-
Vanderlaag, Kathy; Su, Yunpeng; Frankel, Arthur E; Burghardt, Robert C; Barhoumi, Rola; Chadalapaka, Gayathri; Jutooru, Indira; Safe, Stephen (BMC Cancer, 2010)
-
Tang-Quan, Karis Rachel (2019-07-16)Cardiovascular diseases that often result in end-stage heart failure continue to disable and take patient lives around the world. In an effort to provide new therapeutic options for patients waiting for a heart transplant, ...
-
Lee, Je Hoon (2013-05-08)In ruminants, prostaglandin F2 alpha (PGF2α) is released from the endometrium in a pulsatile pattern at the time of luteolysis. The luteolytic PGF2α pulses are transported from the uterus to the corpus luteum (CL) through ...
-
Frank-Cannon, Tamy Catherine (Texas A&M University, 2006-04-12)Mutations of the á1A subunit of P/Q-type voltage-gated calcium channels are responsible for several inherited disorders affecting humans, including familial hemiplegic migraine, episodic ataxia type 2 and spinocerebellar ...
-
Frank, James William (2015-05-12)Establishment of a successful pregnancy is dependent upon proper communication between the conceptus and uterus and provides the critical physiological and anatomical groundwork required to maintain growth and development ...
-
Hedrick, Erik Duane (2016-12-13)The orphan nuclear receptor 4A1 (NR4A1) and specificity protein (Sp) transcription factors (TFs) are both overexpressed in the majority of solid tumors. Our laboratory has researched the molecular mechanisms of a novel ...
-
Kolar, Satya Sree N. (2009-05-15)Docosahexaenoic acid (DHA, 22:6n-3) from fish oil, and butyrate, a short-chain fatty acid fiber-fermentation product, protect against colon tumorigenesis in part by coordinately inducing apoptosis. We have demonstrated ...
-
Kramer, Avery Christine (2021-12-08)The swine industry experiences high rates of embryonic/fetal loss and there is considerable variation of birthweight between piglets within a litter. These outcomes negatively impact the swine industry’s overall efficiency ...
-
Li, Xi (2014-05-07)Cancer accounts for one in eight deaths worldwide and one in four deaths in the United States. Chemotherapy is the most common treatment option for cancer; however, many chemotherapeutic drugs have toxic side effects. Our ...
-
Ramachandran Nair Vasanthakum, Vijayalekshmi (2014-08-13)Cancer is the second leading cause of death worldwide and epidemiological studies suggest the association of diabetes mellitus with an enhanced risk for multiple cancers. Metformin (1,1-dimethylbiguanide hydrochloride) is ...
-
Tang, Leung Kau (2017-05-05)Angiogenesis, the formation of new blood vessels from pre-existing ones, plays a crucial role in physiological processes and various pathological conditions including cancer. Angiogenic factor stimulation, including ...
-
Krishnaveni Sivakumar, Kirthiram (2018-07-31)Environmental exposure to endocrine-disrupting chemicals (EDCs) is one of the causes of premature ovarian failure (POF). Hexavalent chromium (CrVI) is a heavy metal EDC widely used in more than 50 industries, including ...
-
Duran, Camille L (2017-04-18)A hallmark of high grade glioma is highly aggressive, diffuse invasion into normal brain tissue, contributing to a 100% recurrence rate and resistance to current therapies. Recent efforts to determine molecular differences ...
-
Hosako, Hiromi (2009-05-15)In the studies described in this dissertation, we investigated the roles of p53 in normal development, teratogen-induced apoptosis, and birth defects. In the first study, the activation of p53 and its target genes, p21, ...
-
Halloran, Katherine Marie (2022-04-14)The mammalian embryo must develop from a single cell (the oocyte fertilized by the sperm) to a multi-cellular fetal-placental unit. In particular, the conceptuses (embryo/fetus and associated placental membranes) of livestock ...
-
Khalaf, Omar (2019-11-12)Osteoarticular brucellosis is the most common complication in Brucella-infected humans. The mechanism of bone destruction caused by Brucella remains partially unknown due to the lack of a suitable animal model. Of greater ...
-
Wing, Theodore (2013-11-22)During pregnancy, uterine and placental blood vessels develop to facilitate maximal transfer of nutrients to the fetus. These studies focus on the incorporation of endothelial progenitor cells (EPCs) into the growing ...
-
Behlen, Jonathan Charles (2022-03-29)Particulate matter (PM) air pollution is of growing concern due to increasing evidence of its ability to cause adverse health effects, particularly during development. PM represents a heterogenous mixture of compounds ...
-
Gao, Yang (2017-07-14)Transforming growth factor beta (TGFβ) superfamily signaling regulates multiple reproductive events. However, the in vivo role of the TGFβ signaling in uterine development and function is not well defined. Conditional ...
-
Bazer, Fuller W; Song, Gwonhwa; Kim, Jinyoung; Dunlap, Kathrin A; Satterfield, Michael Carey; Johnson, Gregory A; Burghardt, Robert C; Wu, Guoyao (Journal of Animal Science and Biotechnology, 2012)