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dc.creatorWalker, Ellen Marieen_US
dc.date.accessioned2013-02-22T20:41:30Z
dc.date.available2013-02-22T20:41:30Z
dc.date.created2001en_US
dc.date.issued2013-02-22
dc.identifier.urihttp://hdl.handle.net/1969.1/ETD-TAMU-2001-Fellows-Thesis-W2526en_US
dc.descriptionDue to the character of the original source materials and the nature of batch digitization, quality control issues may be present in this document. Please report any quality issues you encounter to digital@library.tamu.edu, referencing the URI of the item.en_US
dc.descriptionIncludes bibliographical references (leaf 15).en_US
dc.description.abstractEdema, increased tissue fluid volume, may be caused by impaired lymphatic system return. This edema formation inhibits organ function. We hypothesized that increased lymphatic fluid protein concentration would cause increased resistance to flow through lymphatic vessels. Mesenteric lymphatic vessels in anesthetized sheep were catheterized at both ends and connected to polyethylene tubing that functioned as inflow and outflow ports. Outflow pressure and, thus, the end-to-end pressure gradient were manipulated by altering the height of the outflow port. Two fluids - lactated Ringers solution and 6% albumin in lactated Ringers solution - were introduced alternately into the vessels. Flow through the vessel was determined for several pressure gradients. We calculated the resistance for each solution using the inverse of the slope of the flow-pressure gradient relationship. The calculated resistance for the Lactated-Ringers solution was 1.796 ± 0.213 mmHgṁin/ml while the resistance for the 6% albumin solution was 1.911 ± 0.154 mmHgṁin/ml. The resistance calculated for the 6% albumin solution was greater in all experiments, however the difference in resistance between the two solutions was not statistically significant (P = .201). We conclude that the number of experiments included in this study was insufficient to resolve the nature of the relationship between protein concentration and resistance in lymphatic vessels.en_US
dc.format.mediumelectronicen_US
dc.format.mimetypeapplication/pdfen_US
dc.language.isoen_USen_US
dc.publisherTexas A&M Universityen_US
dc.rightsThis thesis was part of a retrospective digitization project authorized by the Texas A&M University Libraries in 2008. Copyright remains vested with the author(s). It is the user's responsibility to secure permission from the copyright holder(s) for re-use of the work beyond the provision of Fair Use.en_US
dc.subjectbiomedical science.en_US
dc.subjectMajor biomedical science.en_US
dc.titleThe effect of lymphatic fluid protein concentration on lymphatic resistanceen_US
thesis.degree.departmentbiomedical scienceen_US
thesis.degree.disciplinebiomedical scienceen_US
thesis.degree.nameFellows Thesisen_US
thesis.degree.levelUndergraduateen_US
dc.type.genrethesisen_US
dc.type.materialtexten_US
dc.format.digitalOriginreformatted digitalen_US


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