Now showing items 1-4 of 4

    • Impact of Hyperinsulinemic Priming on Macrophage Activation 

      Jones, Benjamin T (2014-09-18)
      The impact of hyperinsulinemia on adipose tissue inflammation has been studied for decades in order to try and obtain a better understanding of the underlying effects of cardiovascular diseases and diabetes mellitus. Despite ...
    • Interferon Regulatory Factor 6 Regulates Macrophage Polarization 

      Brehm, Tyler Jirush (2014-08-15)
      Under obese stress, adipose tissue macrophages (ATMs) undergo a phenotypic switch from anti-inflammatory status (M2) to proinflammatory (M1) status, a major contributor to the development of chronic tissue inflammation and ...
    • MiR-150, A Novel and Potent Regulator for MLL-AF9 Leukemic Stem Cells 

      Cheruku, Patali (2013-02-18)
      MicroRNAs (miRNAs) are a class of short, non-coding RNAs that post-transcriptionally regulate gene expression, particularly in cancers. MicroRNA-150 has been proven as a critical regulatory for normal hematopoiesis and a ...
    • The Impact of Polarized Activated Macrophages on Adipogenesis 

      Splawn, Taylor Gabriella (2014-09-04)
      Adipose tissue plays a major role in energy storage and Adipokine secretion to maintain systemic balance. However, adipocytes that experience hypertrophy or hyperplasia have negative effects on the processes of obesity-associated ...