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Altered Amino Acid Sequence Affects Amyloid Formation In Aβ(25-35)
Many neurodegenerative diseases are associated with protein misfolding where the protein forms β-sheet rich polymers called amyloid. Alzheimer’s disease (AD) is an amyloid aggregation disease involving the Aβ(1-42) peptide ...
Effect of Amino Acid Subsititution in Set1 on Histone H3 Methylation and Gene Silencing in Saaccharomyces Cerevisiae
Chromosomal DNA in our cells is wrapped around a histone protein octomer like thread on a spool, forming a structure called a nucleosome. Series of nucleosomes form the nuclear chromosomes found in all eukaryotic organisms. ...