Browsing Colleges and Schools by Department "Biomedical Sciences"
Now showing items 1-20 of 52
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(2022-12-12)During C. elegans development, EGF signal from the anchor cell (AC) induces the roughly six equipotent vulval precursor cells (VPCs) to assume the pattern 3˚-3˚-2˚-1˚-2˚-3˚ of cell fates. The VPC closest to the AC is induced ...
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(2022-07-29)Trauma to the orbital region accounts approximately for 3% of all craniofacial injuries, with a mean hospitalization cost of US$ 35,500 per case. Management of orbital fractures is challenging as a substantial amount of ...
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(2015-08-10)Endothelin receptor A (Ednra) signaling pathway is involved in many pathological and physiological conditions, yet the pathway and the genes regulated by the pathway remain largely unknown. Ednra mutant murine embryos are ...
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(2021-04-16)The objectives of the present study were first, to synthesize the literature pertaining to artificial intelligence (AI) and machine learning (ML) applications in orthodontics, second to evaluate the possibility of predicting ...
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(2019-07-29)The osteon (Haversian system) is the basic structural and functional unit of cortical bones in human and many other large mammals like dogs and cows. Different from mouse cortical bones consisting of uniform lamellar bones, ...
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(2020-09-15)The periodontal ligament of humans is a unique organ, a thin membrane of non-ossified connective tissue sandwiched between two active mineralization fronts. Factors such as oral hygiene, tobacco smoking, and pathogenic ...
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(2018-05-09)Background: The periodontal ligament is known to play a role in the bone remodeling response to orthodontic tooth movement and to contribute specifically to osteogenic cell populations involved in this process. Cell lineage ...
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(2020-07-01)The purpose of this project was to determine the cell origins and to investigate the histochemical properties of the products present in adenomatoid odontogenic tumor (AOT). In 1992, the World Health Organization (WHO) ...
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(2017-05-04)Regenerative endodontics is one of the most exciting new developments in endodontics. Pulp regeneration can be achieved basically by using a triad of a reliable cell source capable of differentiating, a suitable scaffold, ...
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(2014-05-06)DMP1, dentin matrix protein 1, was cloned from a rat dentin cDNA library 20 years ago. Initially, this non-collagenous matrix protein was thought to be dentin specific and gained little interest in other scientific communities ...
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(2014-05-06)p27 is a critical CDK inhibitor involved in cell cycle regulation, but its response to DNA damage remains unclear. Constitutive photomorphogenesis 1 (COP1), a p53- targeting E3 ubiquitin ligase, is downregulated by DNA ...
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Dynorphin Promotes Comorbid Migraine-like Pain in Female Mice with Temporomandibular Joint Disorders (2020-07-16)Migraine is a prevailing type of neurological disorder and is frequently found coexisting with temporomandibular disorders (TMD) in the same individual, especially in the patients with myogenic TMD. Both conditions have a ...
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(2017-04-28)This study was designed to observe the effects of an antioxidant gel on oxidative stress levels and salivary flow rates in xerostomic patients. In this prospective, nested, double blind, crossover, randomized clinical ...
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(2014-12-12)Cholangiocarcinoma (CCA) is a devastating tumor characterized by late presentation of symptoms with limited treatment options. Disruption of circadian rhythm is associated with cancer development and progression. MicroRNAs ...
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(2020-07-21)Background: Gingivitis in the geriatric population is a growing public health concern. Finding an effective non-invasive approach to prevent and treat gingivitis is crucial and challenging. It was evident in many studies ...
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(2018-05-03)Calcium (Ca^2+) acts as a universal second messenger to regulate a myriad of biological processes, including gene expression, cell metabolism, lymphocyte activation and cell growth. In non-excitable cells such as cells of ...
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(2018-11-27)HER2-postive breast cancer constitutes approximately 25% of breast cancer patients and leads to a worse prognosis. Antibody therapy, such as the anti-HER2 antibody trastuzumab, is used in the clinical setting to treat these ...
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(2015-04-23)Cleft palate (CP) is one of the most common birth defects. It may not be life threatening but many functions, such as feeding, digestion, speech, middle-ear ventilation, hearing, respiration, and facial and dental development, ...
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(2021-08-13)Skeletal growth deficiencies arising from birth defects, injury or disease exist despite advances in therapy; as a public health imperative, this reflects the need for a deeper understanding of its causes. The molecular ...
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(2021-09-01)Epigenetic alterations, such as changes in DNA methylation, histones/chromatin structure, nucleosome positioning, and expression of non-coding RNAs, are recognized among key characteristics of carcinogens; they may occur ...