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Feline CTLA-4 nucleic acid and polypeptides

dc.creatorCollisson, Ellen W.
dc.creatorChoi, Insoo
dc.creatorWinslow, Barbara J.
dc.creatorCochran, Mark D.
dc.date.accessioned2019-06-17T17:04:55Z
dc.date.available2019-06-17T17:04:55Z
dc.date.issued2010-06-29
dc.identifier.urihttps://hdl.handle.net/1969.1/176929
dc.description.abstractThe present invention provides isolated and purified DNA encoding feline CD80 (B7-1) ligand, feline CD86 (B7-2) ligand, feline CD28 receptor, or feline CTLA-4 (CD152) receptor, as well as vectors comprising nucleic acid encoding feline CD80, feline CD86, feline CD28, or feline CTLA-4. The present invention provides a host cells transformed with CD80-encoding vectors, CD86-encoding vectors, CD28-encoding vectors, or CTLA-4-encoding vectors. The invention provides polypeptides encoded by the nucleic acid of feline CD80, feline CD86, feline CD28, or feline CTLA-4. The present invention provides a vaccine comprising an effective amount of polypeptides encoded by the nucleic acid of feline CD80, feline CD86, feline CD28, or feline CTLA-4. The present invention also provides vaccines which further comprise immunogens derived from pathogens. The invention provides for vaccines capable of enhancing an immune response. The invention also provides for vaccines capable of suppressing and immune response.en
dc.languageeng
dc.publisherUnited States. Patent and Trademark Office
dc.rightsPublic Domain (No copyright - United States)en
dc.rights.urihttp://rightsstatements.org/vocab/NoC-US/1.0/
dc.titleFeline CTLA-4 nucleic acid and polypeptidesen
dc.typeUtility patenten
dc.format.digitalOriginreformatted digitalen
dc.description.countryUS
dc.contributor.assigneeTexas A&M University System
dc.contributor.assigneeIntervet Inc.
dc.identifier.patentapplicationnumber11/414707
dc.subject.uspcprimary536/23.1
dc.subject.uspcother435/320.1
dc.date.filed2006-04-27
dc.publisher.digitalTexas A&M University. Libraries
dc.subject.cpcprimaryA61P 37/04
dc.subject.cpcprimaryA61P 37/06
dc.subject.cpcprimaryA61K 39/39
dc.subject.cpcprimaryC07K 14/70532
dc.subject.cpcprimaryA61K 38/00
dc.subject.cpcprimaryA61K 2039/55516


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