Polypeptides and polynucleotides from coagulase-negative staphylococci
Abstract
Methods for treating or preventing infections from coagulase-negative staphylococci using proteins and polypeptides from coagulase-negative staphylococcal bacteria such as S. epidermidis, including proteins designated SdrF, SdrG and SdrH, and their effective fragments such as their respective A domains, are provided. Methods are also provided wherein antibodies that recognize the SdrG protein or its ligand binding A region are used to treat or prevent staphylococcal infection, and these methods can also be utilized to prevent the formation of infections on indwelling medical devices.
Subject
424/243.1435/69.3
435/252.3
435/470
530/350
536/23.7
A61P 9/00
A61P 17/02
A61P 31/04
C07K 16/1271
C07K 14/31
G01N 33/56938
A61P 19/00
A61K 2039/505
A61K 39/00
Collections
Citation
Foster, Timothy J.; Mccrea, Kirk; Hook, Magnus A. O.; Davis, Stacey; Ni Eidhin, Deirdre; Hartford, Orla (2010). Polypeptides and polynucleotides from coagulase-negative staphylococci. United States. Patent and Trademark Office; Texas A&M University. Libraries. Available electronically from https : / /hdl .handle .net /1969 .1 /176925.