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dc.creatorGuo, Betty P.
dc.creatorHook, Magnus
dc.date.accessioned2019-06-17T16:55:53Z
dc.date.available2019-06-17T16:55:53Z
dc.date.issued2001-04-10
dc.identifier.urihttp://hdl.handle.net/1969.1/176659
dc.description.abstractDisclosed are the dbp gene and dbp-derived nucleic acid segments from Borrelia burgdorferi, the etiological agent of Lyme disease, and DNA segments encoding dbp from related borrelias. Also disclosed are decorin binding protein compositions and methods of use. The DBP protein and antigenic epitopes derived therefrom are contemplated for use in the treatment of pathological Borrelia infections, and in particular, for use in the prevention of bacterial adhesion to decorin. DNA segments encoding these proteins and anti-(decorin binding protein) antibodies will also be of use in various screening, diagnostic and therapeutic applications including active and passive immunization and methods for the prevention of Borrelia colonization in an animal. These DNA segments and the peptides derived therefrom are contemplated for use in the preparation of vaccines and, also, for use as carrier proteins in vaccine formulations, and in the formulation of compositions for use in the prevention of Lyme disease.en
dc.languageeng
dc.publisherUnited States. Patent and Trademark Office
dc.rightsPublic Domain (No copyright - United States)en
dc.rights.urihttp://rightsstatements.org/vocab/NoC-US/1.0/
dc.titleDbpA compositionsen
dc.typeUtility patenten
dc.format.digitalOriginreformatted digitalen
dc.description.countryUS
dc.contributor.assigneeTexas A & M University System
dc.identifier.patentapplicationnumber09/117257
dc.subject.uspcprimary424/234.1
dc.subject.uspcother514/2.8
dc.subject.uspcother530/350
dc.subject.uspcother530/388.4
dc.date.filed1998-07-22
dc.publisher.digitalTexas A&M University. Libraries


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