Now showing items 1-4 of 4
Antibodies recognizing a highly expressed putative antigen of CA-MRSA and methods of use
(United States. Patent and Trademark Office, 2012-02-28)
The present invention provides MSCRAMM® proteins from S. aureus which are putative highly-expressed antigens from methicillin-resistant S. aureus, including communit-associated MRSA (CA-MRSA), and these antigens can thus ...
Crystal structure of Staphylococcus aureus clumping factor A in complex with fibrinogen derived peptide and uses thereof
(United States. Patent and Trademark Office, 2012-10-02)
The present invention provides a method for determining the structure of a microbial surface components recognizing adhesive matrix molecule in complex with fibrinogen, by providing a ClfA complexed with a fibrinogen ...
Specific binding sites in collagen for integrins and use thereof
(United States. Patent and Trademark Office, 2012-08-28)
The present invention identified a high affinity binding sequence in collagen type III for the collagen-binding integrin I domains. Provided herein are the methods used to characterize the sequence, the peptides comprising ...
Treatment of Staphylococcus aureus infections utilizing antibodies that bind to fibronectin binding proteins
(United States. Patent and Trademark Office, 2012-07-03)
Disclosed are antibodies that block the binding of fibronectin protein to fibronectin. Also disclosed are site specifically-mutated and truncated peptide epitopes derived from the fnbA and fnbB genes of Staphylococcus ...