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Investigation of the Mechanical Characteristics of Medical Device Components, Constructs and Design Support Packages
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The field of biomechanics seeks to explain natural phenomena in the terms of classic engineering. Its theories are commonly applied to the motion and structure of an organism, and from that basis we can analyze and design complex medical components, multi-component constructs and even tools to make that design process or investigative effort easier. This portfolio dissertation concerns the application of biomechanics to the medical device community in six separate projects. The first project concerns the development of a total knee replacement tibial tray bone-implant interface which will eventually be submitted for 510(k) clearance with the FDA. The second project details the proof of concept testing of a regenerative fracture fixation device on a sheep model that eventually biodegrades away, leaving no device left behind. The third project is the investigation of the effects of static and dynamic loading on the degradative properties of PLLA fibers, the information from which will be used to form a computational model simulating that degradation. The fourth project compares the gold standard LCDCP fracture fixation plate to a more versatile CRIF option gaining popularity in the veterinary community. The fifth and final project outlines the development of an electrospinning apparatus that is capable of spinning parallel fibers for investigation into cardiac stem cell therapies. All of these projects illustrate both simple and complex applications of the laws of classic mechanics to the field of medical devices and medical device support packages.
Bergerson, Christine M (2015). Investigation of the Mechanical Characteristics of Medical Device Components, Constructs and Design Support Packages. Doctoral dissertation, Texas A & M University. Available electronically from