THE EFFECTS OF STONE FRUIT EXTRACT ON THE PROCESS OF PLATELET AGGREGATION IN VITRO
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This project attempts to examine the impact stone fruits can have on the clotting of blood in the human body. Plum rich anthocyanin extract (RAE) was added in different concentrations (1-25ug/ml) to rabbit platelets suspended in Tyrode’s buffer and mixed in microplate wells. Platelet aggregation was then induced by 5 uM ADP (Adenosine Diphosphate), and the percent of transmittance was measured by a microplate reader. A change in aggregation of over 10% was recorded. The results suggest that the extract inhibits the aggregation caused by ADP. This would also lead one to believe that there are compounds in stone fruits that could lower the chances of cardiovascular disease by limiting aggregation and subsequently inflammation in arterial walls.
Deleeuw, Peter 1990- (2011). THE EFFECTS OF STONE FRUIT EXTRACT ON THE PROCESS OF PLATELET AGGREGATION IN VITRO. Honors and Undergraduate Research. Available electronically from