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dc.creatorWang, Xi
dc.creatorZhang, Aihua
dc.creatorZhi, Miaochan
dc.creatorSokolov, Alexei V.
dc.creatorWelch, George R.
dc.date.accessioned2011-09-08T21:36:40Z
dc.date.available2011-09-08T21:36:40Z
dc.date.issued2010
dc.identifier.citationXi Wang, Aihua Zhang, Miaochan Zhi, Alexei V. Sokolov and George R. Welch. Phys.Rev.A 81 013813 2010. "Copyright (2010) by the American Physical Society."en
dc.identifier.urihttp://dx.doi.org/10.1103/PhysRevA.81.013813
dc.identifier.urihttps://hdl.handle.net/1969.1/126638
dc.descriptionJournals published by the American Physical Society can be found at http://publish.aps.org/en
dc.description.abstractWe investigate the possibility of using a hybrid coherent anti-Stokes Raman scattering technique for noninvasive monitoring of blood glucose levels. Our technique combines instantaneous coherent excitation of several characteristic molecular vibrations with subsequent probing of these vibrations by an optimally shaped, time-delayed, narrowband laser pulse. This pulse configuration mitigates the nonresonant four-wave mixing background while maximizing the Raman-resonant signal and allows rapid and highly specific detection even in the presence of multiple scattering. Under certain conditions we find that the measured signal is linearly proportional to the glucose concentration due to optical interference with the residual background light, which allows reliable detection of spectral signatures down to medically relevant glucose levels.en
dc.language.isoen
dc.publisherAmerican Physical Society
dc.subjectSPECTROSCOPYen
dc.subjectOpticsen
dc.subjectPhysicsen
dc.titleGlucose concentration measured by the hybrid coherent anti-Stokes Raman-scattering techniqueen
dc.typeArticleen
local.departmentPhysics and Astronomyen


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