Browsing by Subject "Zebrafish"
Now showing items 1-10 of 10
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(2017-04-24)Thyroid hormones regulate essential physiological processes, including metabolism, reproduction, and growth. A key constituent of all thyroid hormones is iodine. To obtain and concentrate iodine, vertebrates utilize a ...
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Bisphenol A (BPA), a common environmental toxicant and endocrine disrupting chemical, is becoming increasingly important due to its potential carcinogenicity. The aim of this research project was to study the effects of ...
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(2015-11-10)Sox genes encode transcription factors that function as part of a complex gene regulatory network governing development of the otic placode, the precursor of the inner ear. Sox genes have been implicated in maintaining ...
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(2010-07-14)Vertebrate photoreceptors are highly specialized sensory neurons that utilize a modified cilium known as the outer segment to detect light. Proper trafficking of proteins to the outer segment is essential for photoreceptor ...
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(2009-05-15)Eukaryotic transcriptional activators stimulate transcription of genes otherwise expressed at low levels. The typical activator operates by binding to specific sites on DNA with its activating region contacting the ...
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(2012-10-19)In vertebrates, the otic placode forms inner ear and epibranchial placodes produce sensory ganglia within branchial clefts. Fibroblast growth factor (FGF) family of protein ligands from the surrounding tissues are responsible ...
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(2017-05-08)The Midbrain Hindbrain Domain (MHD) is a region of the central nervous system consisting of the midbrain, midbrain hindbrain boundary (MHB) and anterior hindbrain. The MHB is an organizer that patterns the midbrain and ...
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(2016-05-24)We set out to characterize a population of midbrain fluorescing cells in zebrafish that appeared to be of melanophore lineage and in doing so discovered a potential role for sox10 expression in the zebrafish central nervous ...
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(2020-08-19)Zinc Finger Protein 143 (ZNF143) is a ubiquitous C2H2 zinc-finger transcriptional activator in vertebrates. Predicted to regulate over 2000 promoters, ZNF143 activates transcription at both protein coding genes and small ...
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(2017-05-30)This study assesses the importance of enhancers of wnt genes- wnt1 and wnt10b during midbrain hindbrain boundary formation in zebrafish. These cis-regulatory elements are hypothesized to regulate wnt1 and wnt10b transcription ...