Browsing by Subject "NR4A1"
Now showing items 1-4 of 4
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(2016-12-13)The orphan nuclear receptor 4A1 (NR4A1) and specificity protein (Sp) transcription factors (TFs) are both overexpressed in the majority of solid tumors. Our laboratory has researched the molecular mechanisms of a novel ...
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(2014-05-07)Cancer accounts for one in eight deaths worldwide and one in four deaths in the United States. Chemotherapy is the most common treatment option for cancer; however, many chemotherapeutic drugs have toxic side effects. Our ...
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(2017-08-03)Rhabdomyosarcoma (RMS) is a pediatric cancer for which common therapeutics include cytotoxic chemotherapeutics that result in adverse health outcomes later in adulthood. Previous studies have found NR4A1 expression contributes ...
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(2023-08-04)NR4A subfamily is a group of orphan nuclear receptors with no known endogenous ligands and includes three members: NR4A1, NR4A2, and NR4A3. NR4A members play important roles in maintaining cellular hemostasis and are ...