Browsing by Subject "Methylation"
Now showing items 1-2 of 2
-
Effect of Amino Acid Subsititution in Set1 on Histone H3 Methylation and Gene Silencing in Saaccharomyces Cerevisiae
(2008-08-24)Chromosomal DNA in our cells is wrapped around a histone protein octomer like thread on a spool, forming a structure called a nucleosome. Series of nucleosomes form the nuclear chromosomes found in all eukaryotic organisms. ... -
Engineered Split-TET2 Enzyme for Inducible Epigenetic Remodeling
(2017-12-12)The conversion of 5-methylcytosine (5mC) into 5-hydroxymethylcytosine (5hmC) and further oxidized species is catalyzed by the Ten-eleven translocation (TET) methylcytosine dioxygenase. Here we provided a temporal control ...