Now showing items 1-9 of 9

    • Biosensor compositions and methods of use 

      Bayley, Hagan P.; Howorka, Stefan G.; Movileanu, Liviu (United States. Patent and Trademark OfficeTexas A&M University. Libraries, 2005-07-12)
      Provided are pore-subunit polypeptides covalently linked to one or more sensing moieties, and uses of these modified polypeptides to detect and/or measure analytes or physical characteristics within a given sample.
    • Decorin binding protein compositions and methods of use 

      Guo, Betty P.; Hook, Magnus (United States. Patent and Trademark OfficeTexas A&M University. Libraries, 2001-06-19)
      Disclosed are the dbp gene and dbp-derived nucleic acid segments from Borrelia burgdorferi, the etiological agent of Lyme disease, and DNA segments encoding dbp from related borrelias. Also disclosed are decorin binding ...
    • Feline pancreatic lipase composition and method of preparing and using such composition 

      Steiner, Jorg M.; Williams, David A. (United States. Patent and Trademark OfficeTexas A&M University. Libraries, 2005-02-15)
      A novel form of lipase, namely feline pancreatic lipase (also termed feline classical pancreatic lipase) has an N-terminal amino acid sequence as shown in SEQ ID NO. 1. A method of purifying this lipase includes collecting ...
    • High temperature ion channels and pores 

      Kang, Xiaofeng; Gu, Li Qun; Cheley, Stephen; Bayley, Hagan (United States. Patent and Trademark OfficeTexas A&M University. Libraries, 2011-01-11)
      The present invention includes an apparatus, system and method for stochastic sensing of an analyte to a protein pore. The protein pore may be an engineer protein pore, such as an ion channel at temperatures above 55° C. ...
    • Lipoprotein fingerprinting methods using metal ion chelate salts 

      Macfarlane, Ronald D.; Hosken, Brian D.; Farwig, Zachlyn N.; Espinosa, Irma L.; Myers, Christine L.; Cockrill, Steven L. (United States. Patent and Trademark OfficeTexas A&M University. Libraries, 2008-01-22)
      Methods are disclosed which separate and identify lipoproteins in biological samples. An ultracentrifuge density gradient is used to separate lipoprotein fractions. The fractions are visualized, resulting in a lipoprotein ...
    • Methods for detecting molecule-molecule interactions with a single detection channel 

      Kameoka, Jun; Jing, Nan; Hung, Mien-chie; Chou, Chao-kai (United States. Patent and Trademark OfficeTexas A&M University. Libraries, 2013-11-19)
      A single molecule or molecule complex detection method is disclosed in certain aspects, comprising nano- or micro-fluidic channels.
    • Peptide inhibitor of fibrinogen blood clotting 

      Hook, Magnus A.; Yang, Vivian W-c (United States. Patent and Trademark OfficeTexas A&M University. Libraries, 2002-07-02)
      A method of inhibiting fibrin clot formation is provided. The decorin protein, peptide, or related fragments are found to bind fibrinogen in the presence of Zinc (Zn2+), thus preventing the formation of fibrin clots. The ...
    • Specific binding sites in collagen for integrins and use thereof 

      Xu, Xuejun; Hook, Magnus; Kim, Jiyeun (United States. Patent and Trademark OfficeTexas A&M University. Libraries, 2009-04-07)
      The present invention identified a high affinity binding sequence in collagen type III for the collagen-binding integrin I domains. Provided herein are the methods used to characterize the sequence, the peptides comprising ...
    • Stochastic sensing through covalent interactions 

      Bayley, Hagan; Shin, Seong-ho; Luchian, Tudor; Cheley, Stephen (United States. Patent and Trademark OfficeTexas A&M University. Libraries, 2013-03-26)
      A system and method for stochastic sensing in which the analyte covalently bonds to the sensor element or an adaptor element. If such bonding is irreversible, the bond may be broken by a chemical reagent. The sensor element ...