Now showing items 1-12 of 12

    • Bioinformatic method for identifying surface-anchored proteins from gram-positive bacteria and proteins obtained thereby 

      Hook, Magnus; Xu, Yi; Sillanpaa, Jouko V.; Sthanam, Narayana; Ponnuraj, Karthe; Patti, Joseph M.; Hutchins, Jeff T.; Hall, Andrea; Bowden, Maria G. (United States. Patent and Trademark OfficeTexas A&M University. Libraries, 2010-12-14)
      A bioinformatic method is provided for identifying and isolating proteins with MSCRAMM®—like characteristics from Gram positive bacteria, such as Enterococcus, Staphylococcus, Streptococcus and Bacillus bacteria, which can ...
    • Collagen-binding proteins from enterococcal bacteria 

      Rich, Rebecca L.; Kriekemeyer, Bernd; Owens, Rick T.; Hook, Magnus; Murray, Barbara E.; Nallapareddy, Sreedhar R.; Weinstock, George M. (United States. Patent and Trademark OfficeTexas A&M University. Libraries, 2005-06-21)
      A collagen-binding MSCRAMM entitled Ace from enterococcal bacteria is provided which was homologous to the ligand-binding region of Cna, the collagen-binding MSCRAMM from Staphylococcus aureus, and which can be utilized ...
    • Collagen-binding proteins from enterococcal bacteria 

      Rich, Rebecca L.; Kriekemeyer, Bernd; Owens, Rick T.; Hook, Magnus; Murray, Barbara E.; Nallapareddy, Sreedhar R.; Weinstock, George M. (United States. Patent and Trademark OfficeTexas A&M University. Libraries, 2009-12-29)
      A collagen-binding MSCRAMM entitled Ace from enterococcal bacteria is provided which was homologous to the ligand-binding region of Cna, the collagen-binding MSCRAMM from Staphylococcus aureus, and which can be utilized ...
    • Compositions and methods of enhancing immune responses 

      Bottje, Walter; Hargis, Billy; Berghman, Luc; Kwon, Young Min; Cole, Kimberly; Cox, Mandy; Layton, Sherryll (United States. Patent and Trademark OfficeTexas A&M University. Libraries, 2013-12-10)
      Provided herein are Salmonella enteritidis 13A strains and compositions comprising these strains. Also provided are methods of enhancing an immune response against Influenza A and methods of reducing morbidity associated ...
    • DbpA compositions 

      Guo, Betty P.; Hook, Magnus (United States. Patent and Trademark OfficeTexas A&M University. Libraries, 2001-04-10)
      Disclosed are the dbp gene and dbp-derived nucleic acid segments from Borrelia burgdorferi, the etiological agent of Lyme disease, and DNA segments encoding dbp from related borrelias. Also disclosed are decorin binding ...
    • Decorin binding protein compositions and methods of use 

      Guo, Betty P.; Hook, Magnus (United States. Patent and Trademark OfficeTexas A&M University. Libraries, 2001-06-19)
      Disclosed are the dbp gene and dbp-derived nucleic acid segments from Borrelia burgdorferi, the etiological agent of Lyme disease, and DNA segments encoding dbp from related borrelias. Also disclosed are decorin binding ...
    • Decorin binding protein essential peptides and methods of use 

      Hook, Magnus A.; Brown, Eric L. (United States. Patent and Trademark OfficeTexas A&M University. Libraries, 2003-02-11)
      Borrelia burgdorferi, the causative agent of Lyme disease, expresses on its surface a decorin binding protein, DbpA and DbpB. Lysine residues necessary for DbpA binding to decorin and DbpA peptides containing these critical ...
    • Method of preventing T cell-mediated responses by the use of the major histocompatibility complex class II analog protein (map protein) from Staphylococcus aureus 

      Brown, Eric; Lee, Lawrence; Hook, Magnus (United States. Patent and Trademark OfficeTexas A&M University. Libraries, 2006-12-26)
      A method of immunomodulating the T cell response in Staphylococcal bacteria is provided wherein an effective amount of the Map protein from Staphylococcus aureus is administered to a host to prevent or suppress the T cell ...
    • Method to produce granulocyte colony stimulating factor from immortalized avian T lymphocytes to produce immortalized cells 

      Kogut, Michael H.; Deloach, John R.; Stanker, Larry H.; Moyes, Rita B.; Hargis, Billy M. (United States. Patent and Trademark OfficeTexas A&M University. Libraries, 1999-04-06)
      Immortal avian T lymphocyte cell lines which produce and secrete immune lymphokines are disclosed. These cell lines may be produced from T cells recovered from fowl which have been hyperimmunized in vivo. The activated T ...
    • Multicomponent vaccines 

      Patti, Joseph M.; Foster, Timothy J.; Hook, Magnus (United States. Patent and Trademark OfficeTexas A&M University. Libraries, 2004-03-09)
      Multicomponent vaccines are provided which aid in the prevention and treatment of staphylococcal infections and which include certain selected combinations of bacterial binding proteins or fragments thereof, or antibodies ...
    • Recombinant virus expressing foreign DNA encoding feline CD86 and uses thereof 

      Winslow, Barbara J.; Cochran, Mark D.; Hash, Stephen; Choi, Insoo; Collisson, Ellen (United States. Patent and Trademark OfficeTexas A&M University. Libraries, 2007-10-09)
      The present invention involves a recombinant virus which comprises at least one foreign nucleic acid inserted within a non-essential region of the viral genome of a virus, wherein each such foreign nucleic acid encodes a ...
    • Vaccine vectors and methods of enhancing immune responses 

      Berghman, Luc; Bottje, Walter; Hargis, Billy; Layton, Sherryll (United States. Patent and Trademark OfficeTexas A&M University. Libraries, 2015-02-17)
      Provided herein are vaccine vectors including an antigenic polypeptide and an HMGB1 polypeptide present on the surface of the vaccine vector. Compositions comprising the vaccine vectors are also provided and include a ...