Browsing by Department "Biochemistry"
Now showing items 1-20 of 49
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(1993)The Sinclair swine Malignant Melanoma is an interesting model for the study of cancer. This melanoma is a spontaneously initiated and regressing tumor. Macrophages have been shown to be infiltrating the tumor at the time ...
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(1977)Transfer RNA (tRNA) methyltransferases were partially purified from Manduca sexta prepupa larvae and 2-day-old pupae. The purification procedure involved pH 5 precipitation, gel filtration to remove endogenous inhibitors ...
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(1993)Firefly luciferase catalyzes a bioluminescent oxidation of luciferin. During the first step of the reaction, when luciferin interacts with ATP, a molecule of luciferyl adenylate is formed and a molecule of pyrophosphate ...
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(1985)The common marmoset (Callithrix jacchus) was used in a nutritional study of a commercial food source. The marmosets were divided into two groups. Group I was fed a new dry food produced by Purina. Group 2, the control ...
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(1990)The Asp15-->Ala mutant of ribonuclease T1 (RNase T1) was constructed by site-directed mutagenesis, cloned and expressed in Escherichia coli. This mutant was synthesized to determine whether or not the aspartic acid at ...
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(1997)What are the cellular mechanisms that govern when the outgrowing neurite of a neuron will branch? This research analyzed one possible biochemical pathway through which environmental and cellular signals are transduced into ...
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(1977)Nerve Growth Factor (NGF) was isolated and purified from the male mouse submaxillary gland and from lyophilized snake venom. Biological activity, isoelectric point and molecular weight were compared. Mouse NGF showed a ...
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(1997)Neuroblasts in the central nervous system of Drosophila have been increasingly utilized as a model for stem-cell study due to their clearly defined asymmetric division pattern and ease of genetic, cellular, and molecular ...
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(1997)At the ends of chromosomes are short repeated DNA sequences called telomeres that maintain the stability of the chromosome. Telomeres are maintained by a unique ribonuclearprotein called telomerase. Telomerase is developmentally ...
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(1978)The cellular slime mold Dictyostelium discoideum is a good organism for studying the excision repair process. The fungicide benomyl is known to have some unusual mutagenic properties; for this reason, we studied its effects ...
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(1990)The type and amount of a person's dietary fatty acids have been shown to affect the tendency towards thrombogenesis. Diets which are high in polyunsaturated fats tend to reduce the risk of thrombogenesis, and long-chain ...
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(1989)I am investigating the effects of light on the accumulation of mRNA for the atpF and rbcL chloroplast genes. Light exposure affects the expression of some plant genes. Chloroplasts are genetically semi-autonomous when ...
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(1982)Many hormones appear to affect the development of the embryonic central nervous system (CNS), causing either gross morphological defects or subtle changes in the functional maturation of neurons which are manifested as ...
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(1994)The effects of low level lead (Pb) exposure in culture for 3 days on the non-specific ATPase activity of rat C6 glioma cells was studied. Cells were incubated in media containing Pb acetate at a concentration of 10⁻⁶M, ...
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(1987)The effects of expression of the Ha-ras oncogene on the growth of murine 3T3-NR6 fibroblasts were examined. Doubling times and rates of protein synthesis and degradation were measured in six cell lines. Three cell lies ...
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(1991)A new method has been developed for estimating the extinction coefficient for a protein. The only information that is needed is the amino acid composition of the protein, and this is readily available if the gene coding ...
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(1998)Although peroxisomes are essential organelles involved in the conversion of hydrogen peroxide to water, they also contain unique metabolic pathways in lipid metabolism. One of these is the "-oxidation of branched-chain ...
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(1996)Past studies have shown that the promoter of a human U6 small nuclear RNA gene contains two distal elements that increase the transcriptional level of the gene. One of these elements, termed OCT, is an octamer motif that ...
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(1983)Aspartate transcarbamylase (ATCase, EC 2.1.3.2) allosterically modulates de novo pyrimidine biosynthesis in the enteric bacteria. This modulation differs in Escherichia coli and Serratia marcescens, with CTP allosterically ...
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(1995)The tightly linked ripening-inhibitor (rin) and macro calyx (mc) loci represent two important developmental genes in tomato fruit ripening and flower development, respectively. Map-based cloning experiments are currently ...