Browsing by Author "Xu, Yi"
Now showing items 1-20 of 20
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A Family of Structurally Related Secreted Proteins of Staphylococcus aureus
Thomas, Sheila Esther (2019-07-18)The opportunistic pathogen, Staphylococcus aureus (S. aureus) can create a number of infections. The bacterium can assemble a two-layered structure composed of fibrinogen (Fg)/fibrin around itself, called the Fg shield to ... -
Bacillus anthracis Spore Entry into Epithelial Cells Is an Actin-Dependent Process Requiring c-Src and PI3K
Xue, Qiong; Jenkins, Sarah A.; Gu, Chunfang; Smeds, Emanuel; Liu, Qing; Vasan, Ranga; Russell, Brooke H.; Xu, Yi; Lau, Andy T. Y. (PloS One, 2010) -
Bacillus anthracis Spore Surface Protein BclA Mediates Complement Factor H Binding to Spores and Promotes Spore Persistence
Wang, Yanyu; Jenkins, Sarah; Gu, Chunfang; Shree, Ankita; Martinez-Moczygemba, Margarita; Herold, Jennifer; Botto, Marina; Wetsel, Rick; Xu, Yi (PLoS Pathogens, 2016) -
Bioinformatic method for identifying surface-anchored proteins from gram-positive bacteria and proteins obtained thereby
Hook, Magnus; Xu, Yi; Sillanpaa, Jouko V.; Sthanam, Narayana; Ponnuraj, Karthe; Patti, Joseph M.; Hutchins, Jeff T.; Hall, Andrea; Bowden, Maria G. (United States. Patent and Trademark OfficeTexas A&M University. Libraries, 2010-12-14)A bioinformatic method is provided for identifying and isolating proteins with MSCRAMM®—like characteristics from Gram positive bacteria, such as Enterococcus, Staphylococcus, Streptococcus and Bacillus bacteria, which can ... -
Bioinformatic method for identifying surface-anchored proteins from gram-positive bacteria and proteins obtained thereby
Hook, Magnus; Xu, Yi; Sillanpaa, Jouko V.; Sthanam, Narayana; Ponnuraj, Karthe; Patti, Joseph M.; Hutchins, Jeff T.; Hall, Andrea; Bowden, Maria G. (United States. Patent and Trademark OfficeTexas A&M University. Libraries, 2009-11-10)A bioinformatic method is provided for identifying and isolating proteins with MSCRAMM®—like characteristics from Gram positive bacteria, such as Enterococcus, Staphylococcus, Streptococcus and Bacillus bacteria, which can ... -
Characterization of Bacillus anthracis Persistence In Vivo
Jenkins, Sarah A.; Xu, Yi; Driks, Adam (PloS One, 2013) -
Complement Evasion by S. aureus Surface Proteins
Kang, Mingsong (2014-08-28)The complement system, a major component of the innate immunity, is critical for combating microbial infections. It can be activated by three distinct pathways: the classical pathway, the lectin pathway and the alternative ... -
Cross-reactive displacing antibodies from collagen-binding proteins and method of identification and use
Hook, Magnus; Xu, Yi; Speziale, Pietro; Visal, Livia; Casolini, Fabrizia; Patti, Joseph M.; Patel, Pratiksha; Domanski, Paul (United States. Patent and Trademark OfficeTexas A&M University. Libraries, 2007-07-10)Antibodies to the CNA protein and to other regions from the collagen binding domain, including domain CNA19, are provided, and antibodies produced in this manner have been shown to be cross reactive to both Staphylococcus ... -
DISSECTING THE ROLES OF WHIP-TRIM14-PPP6C IN INNATE ANTIVIRAL IMMUNITY AND MYELOID BECLIN1 IN TUMOR IMMUNITY
Tan, Peng (2018-05-07)The innate immune system has the ability to tune the inflammatory environment by modulating pathogen-recognition receptors (PRRs) signaling, which can either induce oncogenic changes or generate antitumor immunity through ... -
Lgr4 in Breast Cancer Stem Cells
Zeng, Li (2014-12-11)Breast cancer is the most commonly diagnosed cancer among American women. G-protein coupled receptors (GPCR) comprise a huge family protein with almost 800 members. GPCRs sense molecules or other stimuli outside the cell, ... -
Molecular characterization of FnBPA-mediated Staphylococcus aureus host interactions
Liang, Xiaowen (2017-12-07)Fibronectin-binding protein A (FnBPA) plays a crucial role in the pathogenesis of Staphylococcus aureus by binding to the host proteins fibronectin (Fn) and fibrinogen (Fg) found in the extracellular matrix and blood plasma, ... -
Prokaryotic collagen-like proteins and uses thereof
Hook, Magnus; Lukomski, Slawomir; Xu, Yi (United States. Patent and Trademark OfficeTexas A&M University. Libraries, 2010-04-20)The present invention provides recombinant triple helical proteins or collagen-like proteins comprising a prokaryotic protein or one or more domains of a prokaryotic protein comprising a collagen-like peptide sequence of ... -
Prokaryotic collagen-like proteins and uses thereof
Hook, Magnus; Lukomski, Slawomir; Xu, Yi (United States. Patent and Trademark OfficeTexas A&M University. Libraries, 2009-06-09)The present invention provides recombinant triple helical proteins or collagen-like proteins comprising a prokaryotic protein or one or more domains of a prokaryotic protein comprising a collagen-like peptide sequence of ... -
Prokaryotic collagen-like proteins and uses thereof
Hook, Magnus; Lukomski, Slawomir; Xu, Yi (United States. Patent and Trademark OfficeTexas A&M University. Libraries, 2007-07-03)The present invention provides recombinant triple helical proteins or collagen-like proteins comprising a prokaryotic protein or one or more domains of a prokaryotic protein comprising a collagen-like peptide sequence of ... -
Prokaryotic collagen-like proteins and uses thereof
Hook, Magnus; Lukomski, Slawomir; Xu, Yi (United States. Patent and Trademark OfficeTexas A&M University. Libraries, 2005-10-11)The present invention provides recombinant triple helical proteins or collagen-like proteins comprising a prokaryotic protein or one or more domains of a prokaryotic protein comprising a collagen-like peptide sequence of ... -
S. epidermidis Cell Wall Anchored Proteins Located in Composite SCCmec Islands
Arora, Srishtee (2017-12-01)Pathogenic bacteria improve their fitness, pathogenicity and virulence by acquisition of mobile genetic elements (MGE). These MGE carry genes for antibiotic resistance, toxins, virulence factors, etc. Staphylococcus ... -
Surface proteins from gram-positive bacteria having highly conserved motifs and antibodies that recognize them
Xu, Yi; Hook, Magnus A. O. (United States. Patent and Trademark OfficeTexas A&M University. Libraries, 2004-09-14)Isolated peptide sequences and proteins containing these sequences are provided which are useful in the prevention and treatment of infection caused by Gram-positive bacteria. The peptide sequences have been shown to be ... -
Surface proteins from gram-positive bacteria having highly conserved motifs and antibodies that recognize them
Xu, Yi; Hook, Magnus A. O. (United States. Patent and Trademark OfficeTexas A&M University. Libraries, 2007-03-27)Isolated peptide sequences and proteins containing these sequences are provided which are useful in the prevention and treatment of infection caused by Gram-positive bacteria. The peptide sequences have been shown to be ... -
Toll-like Receptors are Regulated by an Autophagy Protein MAP1S & TLR-induced Innate Resistance against Flu
Zhang, Yifan (2016-11-30)Toll-like receptors (TLRs) are pattern recognition receptors (PRRs) that recognize pathogen-associated molecular patterns (PAMPs). The recognition leads to the activation of TLR signaling pathway, which initiates innate ... -
Understanding the Structural Basis for Functional Differences in Staphylococcal MSCRAMMS SDRE1 and BBP/SDRE2 and Their Role in Species Tropism
Francis, Mathew Prashanth (2015-04-29)Microbial Surface Components Recognizing Adhesive Matrix Molecules (MSCRAMMs) on Staphylococcus aureus play roles in attachment, invasion and immune evasion. It has been previously reported that bone sialoprotein-binding ...