Browsing by Subject "cancer"
Now showing items 21-29 of 29
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(2015)Colorectal cancer (CRC) is highly preventable when CRC screening is utilized, yet CRC screening completion among African American men is relatively low and their mortality rates remain 50% higher juxtaposed to their White ...
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(2013-03-14)Curcumin is the active component of tumeric, and this polyphenolic compound has been extensively investigated as an anticancer drug that modulates multiple pathways and genes. We demonstrated that curcumin inhibited 253JB-V ...
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(2020-03-26)The research outlined in this proposal has three objectives: (i) to model biological pathways involved in cancer using data and prior knowledge; (ii) to investigate the mechanism of action for drugs that are used in cancer ...
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(2014-07-02)The discovery of the antitumor properties of cisplatin revolutionized the field of medicinal inorganic chemistry and fostered the development of metal-based anticancer drugs, a topic that continues to play a prominent role ...
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(Texas A&M University, 2004-11-15)In a normal microarray classification problem there will be many genes, on the order of thousands, and few samples, on the order of tens. This necessitates a massive feature space reduction before classification can take ...
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(2017-02-17)Cancer cells are known to exhibit atypical metabolic characteristics. While alterations in tumor cell metabolism are necessary for the sustained uncontrolled cell growth that characterizes cancer, it is also a vulnerability ...
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(2021-02-11)Small molecule probe development is pivotal in biomolecular science. Peptidomimetics are generally interesting if they resemble peptides or protein-fragments and display biological activities. To achieve this, it is desirable ...
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(Texas A&M University, 2005-11-01)In order to study the expression of MMP2, MMP 3 and MMP9 in breast cancer brain and lung metastasis, we used a syngeneic rat model of distant metastasis of ENU1564, a carcinogen-induced mammary adenocarcinoma cell line. ...
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(2017-12-06)The selective delivery of radionuclides to cancerous tissues remains a problematic issue. The lack of specificity and sensitivity for many therapeutic and diagnostic strategies limits their safety and efficacy by putting ...