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Verification of DrenchRite TM in small ruminants in Texas
Abstract
gastrointestinal nematodes, i.e., Haemonchus contort-us, Ostertagia circumcircle, and Trichostrongylus spp., to four anthelmintic groups: benzimidazoles, leva-sole, a combination of benzimidazole/levamisole, and avermectins/milbemycins. Two sheep and two goat flocks were used to verify the DrenchRite['rM] larval development assay with results obtained from fecal egg reduction tests (FERT). The two flocks of each species differed in environmental exposure to gastrointestinal nematodes. The flocks were divided into three or four treatment groups: one control (not treated), a benzimidazole-treated group, a levamisole-treated group, and an ivermectin-treated group. Fecal egg reduction tests were performed with each group and correlations between the reduction percentages and the efficacy values obtained from the DrenchRite['rM] manual were used to verify the assay plate. DrenchRite[TM] indicated high resistance to the benzimidazoles in each of the four flocks. This was in agreement with the FERT data, except for Sheep Flock 2 which was moderately resistant. Data from DrenchRite[TM] pertaining to levamisole showed susceptibility for Sheep Flock 1, moderate resistance for Sheep Flock 2, susceptibility for Goat Flock 1, and moderate resistance for Goat Flock 2. The FERT data relative to levamisole showed high resistance for Sheep Flock 1, susceptibility for Sheep Flock 2, high resistance for Goat Flock l, and susceptibility for Goat Flock 2. No benzimidazole/levamisole combination was tested in the four flocks so no comparison was made to the DrenchRite[TM] data. DrenchRite['rM] results for the averments showed susceptibility for Sheep Flock 1, Sheep Flock 2, and Goat Flock 2. Goat Flock 1 was not given any averment-in for the FERT so no comparison was made with the DrenchRite[TM] results. The FERT data for the avermectins exhibited moderate resistance in Sheep Flock 1, high resistance in Sheep Flock 2, and susceptibility in Goat Flock 2. According to the data obtained for these four flocks, DrenchRite['rM] was verified for the benzimidazoles with the exception of Sheep Flock 2. But when compared with the FERT for the other drug groups, no agreement was detected corresponding with the set parameters of resistance levels.
Description
Due to the character of the original source materials and the nature of batch digitization, quality control issues may be present in this document. Please report any quality issues you encounter to digital@library.tamu.edu, referencing the URI of the item.Includes bibliographical references: p. 86-92.
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Citation
Young, Kerry Elaine (1998). Verification of DrenchRite TM in small ruminants in Texas. Master's thesis, Texas A&M University. Available electronically from https : / /hdl .handle .net /1969 .1 /ETD -TAMU -1998 -THESIS -Y586.
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